Analysis of spin-trapped free radicals in bacterial cells using mass spectrometry techniques

Entry requirements

Please use this Research Proposal, Personal statement and CV writing guide when preparing an application.

Months of entry

Anytime

Course content

Reactive oxygen species (ROS), like superoxide and hydrogen peroxide, are formed during aerobic respiration in bacterial cells and may induce oxidative damage, either directly or after formation of even more reactive species including hydroxyl radicals. Spin trapping is a popular technique for the detection of unstable and short-lived free radicals. In this method, free radicals are trapped to produce a stable compound that can then be detected.

The aim of these projects is to detect spin trapped free radicals produced by bacteria using mass spectrometry methods. As part of the project, students will receive training in the handling of bacterial cell cultures and the use of instrumentation such as gas chromatography mass spectrometry (GC-MS) and liquid chromatography mass spectrometry (LC-MS)

Fees and funding

This programme is self-funded.

To enquire about University of Salford funding schemes – including the Widening Participation Scholarship – visit this website.