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Medicinal Chemistry University of Central Lancashire

Department name
School of Pharmacy and Biomedical Sciences
Qualification, duration, mode
MSc 12FT
Months of entry
September
Entry requirements
Entry requirements: a bachelors degree in either Chemistry, Chemical Engineering or a related discipline with a substantial chemical content, for example, Biochemistry or Pharmaceutical Sciences (or overseas equivalent). A 1st or 2nd class degree is normally required. International students should have an English language qualification, IELTS at 6.5, TOEFL at 600 (paper) and 250 (CBE) with a TWE of 4.
Information for International Students
International students should have an English language qualification, IELTS at 6.5, TOEFL at 600 (paper) and 250 (CBE) with a TWE of 4.
Course description
This course is designed for students wishing to pursue either a career in the pharmaceutical industry or an allied discipline. It has been developed with the aim of giving graduates the necessary knowledge and practical skills to become valuable team members within the pharmaceutical industry, with particular emphasis on medicinal and synthetic chemistry. Modules include: Research Methods for Clinical Science : provide the necessary skills in literature-based study, including the use of primary scientific literature. IT and statistical awareness is required to plan scientific experiments and process the data and will also be included within the module. Guidance on finding and using information, including web-based information, scientific communication and citation will be applied to student-centred literature-based exercises. Medicinal Chemistry I: an in-depth understanding of the strategies and techniques involved in drug discovery, design, and development. Includes an overview of drug discovery, design, and development; structure-activity relationships (SAR), lead compounds, pharmacophores, computer-aided drug design and physicochemical properties; stereochemistry; proteomics and combinatorial and parallel synthesis as well as the application of analytical tools. Medicinal Chemistry II: develops in-depth aspects of drug discovery, design and development including pharmacodynamics/pharmacokinetics, structure-based ligand design, quantitative structure-activity relationships, structure-pharmacological property relationships and the application of biocatalysts. The role of enzymes, receptors and nucleic acids as drug targets will be investigated as will different drug forms including an overview of therapeutic agents from nature. Practical Techniques in Industrial/Medicinal Chemistry: focuses on two areas of medicinal chemistry, one covering aspects of pre-formulation of active compounds such as solubility and dissolution determinations, pH solubility profiles, pH stability profiles, partition coefficients, determination of pKa, polymorphism, bioavailability and compatibility studies of actives with specific excipients. Students will have the opportunity to synthesize compounds of interest, characterise them and study their stability in the presence of specific enzymes or reactive reagents. In addition, the student will develop an awareness and understanding of techniques used in automated analysis. The student will have the opportunity to explore and evaluate approaches used in resolving analytical problems and its application to 'real life' situations is the main driving force behind this practical based module. Applied Biopharmaceutics: explores the influence of formulation on the bioavailability of drugs by studying the various routes of drug administration available to the formulation scientist and discussing how the physicochemical properties of a drug influence its bioavailability. Quality Management and Clinical Governance for Biomedical Sciences: aims to provide students with an understanding of quality management and clinical governance and their significance to achieving long term improvements. An insight into Molecular Modelling and its Applications: provides a comprehensive introduction to the strategies and techniques involved in molecular modelling, including virtual screening and similarity searching in lead identification and optimisation. Research Project: housed in the dedicated postgraduate research laboratories. You will carry out a project in an area related to medicinal chemistry for a period of three months full time, using state of the art facilities.
Funding
2012/13 entry full-time postgraduate students will receive a £1000 reduction if in receipt of a UCLan award and are paying the standard or higher full-time fee. If students have a 2:1 or higher then they will receive a further £1000 with a UCLan first degree or £1200 from another University.
New students enrolled annually
unknown
Total enrolled students
unknown
Contact name
Course Enquiries
Contact email
cenquiries@uclan.ac.uk
Contact phone
+44 (0)1772 892400
Contact web
http://www.uclan.ac.uk/information/courses/msc_medicinal_chemistry.php

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